June 24, 2019 § Leave a comment
CHILDHOOD abuse has long been suspected of increasing a person’s risk of developing disease later in life. Now researchers studying inflammation in the bloodstream think they might know why.
Previous studies have suggested that childhood trauma increases a person’s risk of developing heart disease, diabetes and other disorders normally associated with obesity in adulthood.
To investigate further, Andrea Danese at King’s College London and his colleagues monitored 1000 people in New Zealand from birth to the age of 32, noting any factors that created stress, and recorded levels of C-reactive protein in their blood. The protein is a marker of inflammation and has been linked to heart disease.
They found that people who reported having been physically or sexually abused, or rejected by their mothers at a young age, were twice as likely to have significant levels of C-reactive protein in their blood (Proceedings of the National Academy of Sciences, DOI: 10.1073/pnas.0610362104).
Danese believes that stress induces abnormal levels of inflammation in children, which has repercussions in adulthood. “Inflammation is a natural response to physical trauma such as cutting yourself or getting an infection,” he says, “but psychological stress can also trigger inflammation, because stress is really the anticipation of pain.”
He suggests that constant stress could also reduce a child’s ability to produce glucocorticoid hormones, which are the main mechanism the body uses to turn off inflammation. His team now plans further work to measure glucocorticoid levels in people who were exposed to stress during childhood.
“This is much stronger than simply saying that people who have a harder time in childhood are more miserable or depressed as adults,” says Andrew Steptoe at University College London, who has studied the relationship between emotional triggers and heart disease. “They have elegantly connected childhood stress to a real adult risk of disease.”
Danese hopes his work will help people identify those at risk of developing heart disease at an earlier age.
For more information on ACE click here
June 19, 2019 § Leave a comment
ACE aware Scotland just put together the most amazing conference in Glasgow last week. Gabor Mate was the guest speaker the Hungarian-born Canadian physician with a background in family practice and a special interest in childhood development and trauma, and in their potential lifelong impacts on physical and mental health, including on autoimmune disease, cancer, ADHD, addictions and a wide range of other conditions.
I counted 3 standing ovations during the day, amazing considering the bulk of the audience was made up of downtrodden thrid sector / nhs managers. For one day, listening to the speakers, they had hope. Hope that sense would prevail. Gabor spoke about illness caused by exposure to ACE’s and how it manifests itself in later life, in autoimmune diseases, mental health issues and even MS. Dealing with the elephant in the room, the trauma itself rather than the effects of the trauma results in a much better outcome – research led – evidence based. One of the biggest cheers came when Gabor spoke about when he gave evidence to a government committee in the USA. He spoke about ACEs and how we should include an understanding of them in treatment. They didn’t listen and just kept asking the same questions over and over again. Eventually he said ‘you expect me as a physician to practice evidence based medicine, but you don’t practice evidence based politics’.
For more about ACE go to mindschange.co.uk
August 31, 2013 § Leave a comment
Last Night I attended a Girl Geek dinner and networking event. It was absolutely wonderful and inspirational. GirlGeeks.org, encourage women to develop their careers in technology, as well as:
Develop GirlGeeks content for training via classes as well as online and video-based seminars.
Even “after the bubble”, the world is a new place, and technology for communication and community-building are more important than ever. Girl Geeksensure that women and other often-overlooked groups have the freedom, motivation and resources to participate in this new world.
Organised by Morna Simpson founder of FlockEdu.co.uk she introduced the illustrious panel by saying that today the Tech Community in Scotland has developers from a range of backgrounds. Alongside maths, physics and computing graduates, I know linguists who love natural language programming, fine-artists who are into open-source sculptors who develop physics-engines and weavers who do front-end development.
But the digital sector is made up from many more people than that. There is a place for marketing, sales, designers, and a host of others too.At heart many of these people are motivated and united by the idea of building new things that can change the world for the better.
Don’t forget the heroes of digital technology are all visionaries who saw the potential of digital technology to democratise knowledge, create better economic systems and a fairer society.
Girl Geek Scotland is a place where we hope to bring together all of kinds people for inspiring discussion and productive networking.
We are delighted to bring such an influential group of WOMEN together to share their knowledge with Scotland’s current and future entrepreneurs. Now I told you I would give a more detailed introduction to our guests. But honestly each person has such an extensive CV that it could take all night. So instead I have tried to select some highlights for you.
Heidi Roizen, Venture Partner with Draper Fisher Jurvetson and Director for TiVo, Eventful, TrustID, ShareThis and XTime
She is a Venture Partner with leading global venture capital firm Draper Fisher Jurvetson. She is also currently a
corporate director for TiVo (NASDAQ:TIVO), DMGT (LSE:DMGT), Eventful, TrustedID, ShareThis and XTime. Her prior board experience includes Great Plains Software, the Pacific Exchange, the Software Publishers Association and the National Venture Capital Association, in addition to numerous academic and non-profit boards. Roizen also currently teaches the class “Spirit of Entrepreneurship” in the engineering department at Stanford University.
Karen White, President and Chief Operating Officer, Addepar
Karen has spent over 25 years in the technology industry as a successful operating executive and investor focused on enterprise and business software. Karen was most recently CEO and Chairman of Syncplicity, where she grew the company to more than 30,000
business customers over 3 years. Previously, Karen led worldwide corporate and business development at SolarWinds, a top network management software company. She joined the team while they were still privately held and the company debuted its successful IPO in May 2009. Before SolarWinds, Karen served as managing director at Pequot Ventures, a private equity firm with $1.8 billion under
management, where she established and led the software investing team in Silicon Valley.
Ann Winblad, co-founder and Managing Director of Hummer Winblad Venture Partners
Ann Winblad is the co-founder and a Managing Director of Hummer Winblad Venture Partners. Hummer Winblad Venture Partners (www.humwin.com ) is a leading venture capital firm focused on software investing and manages over $1 billion in cumulative capital. Since Hummer Winblad Venture Partners’ inception in 1989 the firm has launched over 100 new software companies.
Wendy Lea, CEO of Get Satisfaction recognised as a Top 100 Woman of Influence in Silicon Valley
Wendy Lea is the CEO of Get Satisfaction. Wendy currently serves as an angel investor, strategic advisor and board
member for a long list of startup companies. Wendy serves on the board of Silicon Valley Social Venture Capital (SV2.org) and Corporate Visions. She has been recognized as a Top 100 Woman of Influence in Silicon Valley and was awarded the Watermark’s “Woman Who Made Her Mark” award.
Dr. Suzanne Doyle-Morris – Chaired the session and
is author of both’ Beyond the Boys’ Club: Strategies for Achieving Career Success as a Woman Working in a Male Dominated Field’ and’ Female Breadwinners: How They Make Relationships Work and Why They are the Future of the Modern Workplace’.
She is a Saltire Fellow has recently founded a new tech company, inclusIQ uses gamified e-learning to help managers reduce unconscious bias in the workplace to create smarter and more competitive teams.
At the end of the night there wasn’t one person who didn’t feel a little more energised, a little more determined to succeed with their venture.
Well done Girl Geeks and well done Morna. I am very much looking forward to the next event.
For information on Courses run by MindsChange Training Company
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December 28, 2012 § Leave a comment
By Pippa Stephens in London
Obesity in human beings could be caused by bacterial infection rather than eating too much, exercising too little or genetics, according to a groundbreaking study that could have profound implications for public health systems, the pharmaceutical industry and food manufacturers.
The discovery in China followed an eight-year search by scientists across the world to explain the link between gut bacteria and obesity.
The bacterium – known as enterobacter – encourages the body to make and store fat, and prevents it from being used, by deregulating the body’s metabolism-controlling genes.
“This is a very important phenomenon,” said Professor Zhao Liping, who with a team at Shanghai Jiao Tong University carried out the research. “It is the last missing piece of evidence bacteria causes obesity.”
Other academics not linked to the project were quick to seize on its potential implications.
Dr David Weinkove, lecturer in biological sciences at Durham University, said: “If obesity is caused by bacteria, it could be infectious and picked up from some unknown environmental factor, or a parent. It might not be behavioural after all.”
Dr Weinkove said Prof Zhao’s research paved a way to intervene in obesity and could allow new drugs to be developed for treatment.
The study was published in the peer-reviewed journal of the International Society for Microbial Ecology.
Governments around the world are grappling with an obesity pandemic. Chronically overweight people are at a greater risk of suffering from a heart attack, cancer, and diabetes.
According to government and academic studies, nearly 50 per cent of all adults in the US and UK will be obese by 2030.
The UK government estimated that the total cost of obesity – the cost of healthcare as well as the wider burden on the economy – could amount to £50bn a year by 2050 if the pandemic was left unchecked, according to a report by the Department for Business, Innovation and Skills.
Although the Shanghai research was on a small scale, it is bound to add to a heated debate between the health profession and food and drink manufacturers and fast-food chains over responsibility for obesity.
Prof Zhao said treatment with a specially developed diet could be cheaper and more effective than surgery for the morbidly obese and could be available within three years.
There are 10 times more microbes than human cells in our bodies and they can be beneficial. There are between 200 and 300 different species in a typical person.
The Shanghai team fed a morbidly obese man a special diet designed to inhibit the bacterium linked to obesity and found that he lost 29 per cent of his body weight in 23 weeks. The patient was prevented from doing any exercise during the trial.
Prof Zhao said such a loss in an obese patient using this diet was unprecedented. The patient also recovered from diabetes, high blood pressure and fatty liver disease.
The diet of whole grains, traditional Chinese medicines and non-digestible carbohydrates changed the pH in the gut which limited the bacterium’s activity.
Enterobacter also release chemicals, called endotoxins, which cause insulin resistance and a slower uptake of glucose from the blood after eating. Patients take longer to feel full, so they eat more.
A control for calorie intake was not possible as administering the diet with normal bacteria would cause unsustainable hunger, as the bacteria stops fat stores being mobilised and satiating the body, Mr Zhao said.
For info on how to get fit go to http://www.hypnosis-glasgow-scotland.co.uk/articles.html
December 23, 2012 § Leave a comment
Mindfulness Training and the Compassionate Brain
Meditation cultivates concentration, empathy, and insight at a neural level.
There is a gamut of recent neuroscientific studies that support the transformative power of mindfulness and compassion meditation. Different types of meditation are being shown to create different changes in the brain. In this entry I will compare different types of meditation and look at the science behind how they cultivate concentration, empathy, and insight at a neural level.
In the wake of the Sandy Hook school shootings, we are all looking for ways that we can stop the violence and bloodshed. One angle that I see is to demystify ‘meditation’ and teach young children simple techniques for practicing mindfulness and compassion directed thought.
The weekend after the shootings in Newtown, Connecticut the Dalai Lama spoke to a gathering of Thai Buddhist monks in New Delhi, India about “Reaching the Same Goal with Different Paths.”
The Dalai Lama said that “In the twenty-first century, even in countries with no previous tradition of Buddhism, interest is growing among ordinary people and scientists. The ethics and discipline described in the Vinaya are the foundation for training both in concentration (shamatha) and insight (vipassana). He clarified that with the help of concentration our mind has the ability to remain still and by applying analysis we achieve understanding.”
“However,” he said, “we must remember the rest of humanity. If we can create a more peaceful world, everyone benefits. And to achieve this I think we need to take a more secular, rather than a religious, approach to fostering ethics. Compassion really brings about inner peace and inner strength. Those who practice compassion become calmer and less subject to fear.”
He backed this up by reporting that scientists have also found that when you have compassion, your physical as well as your mental health improves. In recent years multiple studies have come out showing the benefits of mindfulness and compassion meditation.
Mindfulness Training and the Compassionate Brain
Cultivating empathy through compassion meditation affects brain regions that make a person more sympathetic to other peoples’ mental states. Richard Davidson, the William James and Vilas Research Professor of Psychology and Psychiatry at University of Wisconsin-Madison, is a pioneer in this field of meditation as a tool for brain plasticity. Davidson and associate scientist Antoine Lutz have been working on this research for years.
“Many contemplative traditions speak of loving-kindness as the wish for happiness for others and of compassion as the wish to relieve others’ suffering. Loving-kindness and compassion are central to the Dalai Lama’s philosophy and mission,” says Davidson, who has worked extensively with the Tibetan Buddhist leader. “We wanted to see how this voluntary generation of compassion affects the brain systems involved in empathy.”
Davidson and Lutz’s work suggests that through mindfulness training, people can develop skills that promote happiness and compassion. “People are not just stuck at their respective set points,” Lutz says. “We can take advantage of our brain’s plasticity and train it to enhance these qualities.”
Functional magnetic resonance imaging (fMRI) brain imaging shows that positive emotions such as loving-kindness and compassion can be learned in the same way as playing a musical instrument or being proficient in a sport. The scans revealed that brain circuits used to detect emotions and feelings were dramatically changed in subjects who had extensive experience practicing compassion meditation.
The research suggests that individuals — from children who may engage in bullying to people prone to recurring depression — and society in general could benefit from such meditative practices, says Davidson.
The capacity to cultivate compassion, which involves regulating thoughts and emotions, may also be useful for preventing depression in people who are susceptible to it, Lutz adds.”Thinking about other people’s suffering and not just your own helps to put everything in perspective,” he says, adding that learning compassion for oneself is a critical first step in compassion meditation.
The researchers are interested in teaching compassion meditation to youngsters, particularly as they approach adolescence, as a way to prevent bullying, aggression and violence.
“I think this can be one of the tools we use to teach emotional regulation to kids who are at an age where they’re vulnerable to going seriously off track,” Davidson says. Compassion meditation can be beneficial in promoting more harmonious relationships of all kinds, Davidson adds.
“The world certainly could use a little more kindness and compassion,” he says. “Starting at a local level, the consequences of changing in this way can be directly experienced.”
Various techniques are used in compassion meditation. Controls in the Davidson and Lutz study were asked first to concentrate on loved ones, wishing them well-being and freedom from suffering. After some training, they then were asked to generate such feelings toward all beings without thinking specifically about a particular individual.
Creating Educational Video Games That Foster Empathy
In 2010 Richard Davidson challenged video game manufacturers to develop games that emphasize kindness and compassion instead of violence and aggression.
With a recent grant from the Bill & Melinda Gates Foundation, Davidson is working with Kurt Squire, an associate professor in the School of Education and director of the Games Learning Society Initiative, to design and rigorously test two educational games to help eighth graders develop beneficial social and emotional skills – empathy, cooperation, mental focus, and self-regulation.
“By the time they reach the eighth grade, virtually every middle-class child in the Western world is playing smartphone apps, video games, computer games,” says Davidson. “Our hope is that we can use some of that time for constructive purposes and take advantage of the natural inclination of children of that age to want to spend time with this kind of technology.”
The project grew from the intersection of Davidson’s research on the brain bases of emotion, Squire’s expertise in educational game design, and the Gates Foundation’s interest in preparing U.S. students for college readiness-possessing the skills and knowledge to go on to post-secondary education without the need for remediation.
“Skills of mindfulness and kindness are very important for college readiness,” Davidson explains. “Mindfulness, because it cultivates the capacity to regulate attention, which is the building block for all kinds of learning; and kindness, because the ability to cooperate is important for everything that has to do with success in life, team-building, leadership, and so forth.”
He adds that social, emotional, and interpersonal factors influence how students use and apply their cognitive abilities.
The project will focus on designing prototypes of two games. The first game will focus on improving attention and mental focus, likely through breath awareness.
“Breathing has two important characteristics. One is that it’s very boring, so if you’re able to attend to that, you can attend to most other things,” Davidson says. “The second is that we’re always breathing as long as we’re alive, and so it’s an internal cue that we can learn to come back to. This is something a child can carry with him or her all the time.”
The second game will focus on social behaviours such as kindness, compassion, and altruism. One approach may be to help students detect and interpret emotions in others by reading non-verbal cues such as facial expressions, tone of voice, and body posture.
“We’ll use insights gleaned from our neuroscience research to design the games and will look at changes in the brain during the performance of these games to see how the brain is actually affected by them,” says Davidson. “Direct feedback from monitoring the brain while students are playing the games will help us iteratively adjust the game design as this work goes forward.”
Their analyses will include neural imaging and behavioural testing before, during, and after students play the games, as well as looking at general academic performance.
The results will help the researchers determine how the games impact students and whether educational games are a useful medium for teaching these behaviours and skills, as well as evaluate whether certain groups of kids benefit more than others.
“Our hope is that we can begin to address these questions with the use of digital games in a way that can be very easily scaled and, if we are successful, to potentially reach an extraordinarily large number of youth,” says Davidson.
October 25, 2010 § Leave a comment
For many decades, scientists have been conducting research into fitness and how best to achieve it. Largely, the findings make their way to peer reviewed journals and not as far as the general public other than in dribs and drabs. What’s interesting is that scientists have actually broadly reached a consensus. This article looks at the do’s and don’ts of fitness and busts a few myths along the way.
One of the first studies of fitness was published in 1953. They looked at bus conductors and bus drivers. The results published in the Lancet (vol 265, p1053) showed that the conductors suffered half as many heart attacks as drivers. The link between the sedentary life of the drivers vs the constant climbing of stairs and health was made.
These days, the advice is 150 minutes of moderate exercise a week. Studies suggest that only one third of adults achieve this. This, in spite of fitness and exercise being implicated in the prevention of strokes, cancer, diabetes, liver and kidney disease, osteoporosis, brain disease, dementia and depression.
For the full article follow this link – Hypnosis Glasgow
September 4, 2010 § Leave a comment
Young people deal better with stress than their older counterparts according to Nancy Pachana of the University of Queensland, Australia. In elderly people under stress “there is more low-level anxiety and depression”. Research on rats found that when put in a stressful situation, after two weeks, older rats had much higher levels of the stress hormone, corticosterone than the younger rats. Also, they showed increased activity in the area of the brain associated with anxiety. This may well be due to the NLP anchoring effect. Anchoring, happens when the unconscious mind is exposed to a highly emotional state, extreme happiness, sadness or stress for instance. At that point, the unconscious mind searches the fice senses for the trigger for this particular emotion and neurologically links it to that trigger. It is then primed for the next time. Essentially we get better at doing the emotional state. That’s great in an evolutionary sense if the sight of a tiger will produce an excellent fight or flight response, but not so good in our daily lives in the office.
Having nurtured this ability to produce a highly tuned stress response over the years, Hirotka Shoji of the National Centre for Geriatrics and Gerontology in Obu, Japan suggests that the brains ability to damp down the release of corticosterone is reduced with age.
Dylan Evans in his book “Placebo” highlights the research on baboons which shows that those males at the bottom of the social hierarchy have thickened blood and exhibit behaviours which look very similar to depression. One theory is that this is a prolonged acute phase response to being constantly kicked and scratched. The continual activation of this acute phase response then becomes a way of life. This may explain why humans who are under constant stress may also be in a constant state of acute phase response with the attendant symptoms of sickness behaviour (depression) and thickened blood. Could this be the reason why people suffering from stress and depression are far more likely to die of a heart attack?
The importance of decreasing the stress response in our lives must be our mission. If you are still young, to avoid setting up patterns of behaviour and if you are old because you have a reduced ability to deal with it.
For more information about ways to deal with stress –